Should SDMT substitute for PASAT in MSFC? A 5-year longitudinal study
| Autor: | J. C. Ouallet, Vincent Dousset, E. Salort-Campana, Bruno Brochet, Mathilde Deloire, Klaus G. Petry, M C Bonnet |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
Male medicine.medical_specialty Longitudinal study Multiple Sclerosis Paced Auditory Serial Addition Test Neuropsychological Tests Severity of Illness Index Lesion load Disability Evaluation Predictive Value of Tests Humans Medicine Longitudinal Studies Expanded Disability Status Scale medicine.diagnostic_test business.industry Disease progression Follow up studies Symbol digit modalities test Middle Aged Magnetic Resonance Imaging Surgery Neurology Multiple sclerosis functional composite Disease Progression Female Neurology (clinical) Cognition Disorders business Nuclear medicine Follow-Up Studies |
| Zdroj: | Multiple Sclerosis Journal. 14:1242-1249 |
| ISSN: | 1477-0970 1352-4585 |
| DOI: | 10.1177/1352458508094398 |
| Popis: | Background The multiple sclerosis functional composite (MSFC) includes the Paced Auditory Serial Addition test (PASAT) as a measure of cognition. Objectives and methods We compared the MSFC incorporating the Symbol Digit Modalities test (SDMT) (MSFC [sdmt]) to the usually applied MSFC (MSFC [pasat]) in a sample of 46 ptients with relapsing–remitting MS who were followed over a five-year period. Magnetic resonance imaging was performed at baseline. Results The Expanded Disability Status scale (EDSS) deteriorated significantly over 5 years ( P Conclusion We propose not to substitute PASAT by SDMT in the MSFC but to consider SDMT as a complementary useful approach to evaluate overall MS disease. |
| Databáze: | OpenAIRE |
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