Percutaneous cervical cordotomy for cancer-related pain: prospective multimodal outcomes evaluation
| Autor: | Aimee Doyle, Andreas Goebel, Kate Marley, Manish Gupta, Manohar Sharma |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
medicine.medical_specialty
Percutaneous medicine.medical_treatment Analgesic Medicine (miscellaneous) Outcomes evaluation 03 medical and health sciences 0302 clinical medicine Cordotomy Quality of life Neoplasms medicine Humans Prospective Studies 030212 general & internal medicine Oncology (nursing) business.industry Cancer Cancer Pain General Medicine medicine.disease Medical–Surgical Nursing Opioid 030220 oncology & carcinogenesis Cervical Vertebrae Quality of Life Physical therapy Cancer pain business medicine.drug |
| Zdroj: | BMJ SUPPORTIVE & PALLIATIVE CARE |
| Popis: | BackgroundPercutaneous cervical cordotomy (PCC) offers pain relief to patients with unilateral treatment-refractory cancer-related pain. There is insufficient evidence about any effects of this intervention on patients’ quality of life.MethodComprehensive multimodal assessment to determine how PCC affects pain, analgesic intake and quality of life of patients with medically refractory, unilateral cancer-related pain.This study was set in a multidisciplinary, tertiary cancer pain service. Patient outcomes immediately following PCC were prospectively recorded. Patients were also followed up at 4 weeks.ResultsOutcome variables collected included: background and breakthrough pain numerical rating scores before PCC, at discharge and 4 weeks postprocedure; oral morphine equivalent opioid dose changes, Patient’s Global Impression of Change, Eastern Cooperative oncology group performance status and health related quality of life score, that is, EuroQol-5 dimension-5 level (EQ-5D).ConclusionsDespite significant improvement in pain and other standard outcomes sustained at 4 weeks, there was little evidence of improvement in EQ-5D scores. In patients with terminal cancer, improved pain levels following cordotomy for cancer-related pain does not appear to translate into improvements in overall quality of life as assessed with the generic EQ-5D measure. |
| Databáze: | OpenAIRE |
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