Dilated cardiomyopathy and myocarditis in Kenya: an endomyocardial biopsy study
| Autor: | E. G. J. Olsen, D. Gatei, J. E. Sanderson |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Adult
Cardiomyopathy Dilated Male Pathology medicine.medical_specialty Myocarditis Biopsy Serological evidence Endomyocardial biopsy Leukocyte Count T-Lymphocyte Subsets Idiopathic dilated cardiomyopathy medicine Humans Developing Countries Endocardium medicine.diagnostic_test business.industry Myocardium Dilated cardiomyopathy Middle Aged medicine.disease Inflammatory cell infiltration Kenya Microscopy Electron Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | International Journal of Cardiology. 41:157-163 |
| ISSN: | 0167-5273 |
| DOI: | 10.1016/0167-5273(93)90156-b |
| Popis: | We have studied, by light and electron microscopy, left ventricular endomyocardial biopsy specimens from 18 African patients (14 men) with idiopathic dilated cardiomyopathy in Nairobi. Nine patients (50%) had evidence of healing myocarditis, that is the presence of a mild inflammatory cell infiltration within the myocardium. Interstitial fibrosis was prominent in five patients (28%) and in all 18 specimens there were hypertrophied muscle fibres. Therefore, half of the patients with idiopathic dilated cardiomyopathy had histological signs of a previous myocarditis. There was no serological evidence of a previous or recent coxsackie infection or any other common viral infections. It seems probable that the myocarditis was due to an inappropriate immunological reaction to myocardial muscle. |
| Databáze: | OpenAIRE |
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