Re: Effect of Weight Reduction on the Severity of Lower Urinary Tract Symptoms in Obese Male Patients with Benign Prostatic Hyperplasia: A Randomized Controlled Trial
| Autor: | Phyllis Yin-Ping Yau, Chi-Fai Ng, Edwin Wu, Wing-Yee So, Sidney Kh Yip, Chi Hang Yee |
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| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Urology Lower Urinary Tract Dysfunction Prostatic Hyperplasia 030232 urology & nephrology Severity of Illness Index Body Mass Index law.invention 03 medical and health sciences 0302 clinical medicine Lower Urinary Tract Symptoms Randomized controlled trial law Lower urinary tract symptoms Weight loss Internal medicine Weight Loss medicine Nocturia Humans Obesity Prospective Studies Prospective cohort study Exercise Adrenergic alpha-Antagonists Aged business.industry Middle Aged Hyperplasia medicine.disease Surgery Treatment Outcome Male patient Cohort Quality of Life International Prostate Symptom Score Original Article medicine.symptom business Body mass index |
| Zdroj: | Korean Journal of Urology |
| ISSN: | 1527-3792 0022-5347 |
| DOI: | 10.1016/j.juro.2016.05.019 |
| Popis: | Purpose: We assessed whether weight reduction is an effective intervention for the management of lower urinary tract symptoms (LUTS) and investigated the relationship between obesity and LUTS. Materials and Methods: This was a prospective randomized controlled trial that enrolled obese men older than 50 years with LUTS. The study period was 52 weeks. All patients received standardized alpha-adrenergic blocker therapy for the treatment of benign prostatic hyperplasia (BPH) during the run-in period. Patients were randomized to receive either a standardized prerecorded video program on the general principle of weight reduction or a comprehensive weight reduction program. Patients were assessed at different time points with symptom assessment, uroflowmetry, transrectal ultrasound, and metabolic assessment. Results: Sixty-five patients were allocated to each study arm. After the study period, no significant difference in weight reduction was found between the two arms. When the pre- and postintervention parameters were compared, none were statistically different between the 2 arms, namely nocturia, International Prostate Symptom Score, quality of life assessment, and uroflowmetry parameters. When the whole study population was taken as a single cohort, these parameters were also not significantly different between the group with a body mass index of 25 to |
| Databáze: | OpenAIRE |
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