Two-channel electrochemical immunosensor based on one-step-synthesized AuPt-boron-doped graphene electrode for CA153 detection

Autor: Zehua Chen, Hongji Li, Zheng Chen, Xiuwei Xuan, Baozeng Zhou, Mingji Li
Rok vydání: 2022
Předmět:
Zdroj: Biosensorsbioelectronics. 222
ISSN: 1873-4235
Popis: Herein, a novel dual-channel electrochemical immunosensor was fabricated via vertical growth of AuPt-decorated boron-doped graphene (AuPt-BG) nanosheets as a signal amplification platform to detect cancer antigen 153 (CA153). Highly open, porous AuPt-BG films were synthesized using one-step electron-assisted hot-filament chemical vapor deposition. The Au-Pt alloy nanoparticles were dispersed on BG nanosheets to improve their biocompatibility, and antibodies (Ab) were directly bonded to the AuPt-BG electrode. The architectures enlarged the loading of CA153Ab and efficiently catalyzed the Fe(CN)
Databáze: OpenAIRE