Predicting Humphrey 10-2 visual field from 24-2 visual field in eyes with advanced glaucoma
| Autor: | Yoshio Yamazaki, Aiko Iwase, Makoto Araie, Keiji Yoshikawa, Akiyasu Kanamori, Toshihiro Inoue, Hodaka Nemoto, Ryo Asaoka, Kenji Sugisaki, Shinichiro Ishikawa |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Mean squared prediction error Glaucoma 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine Predictive Value of Tests Ophthalmology medicine Humans Intraocular Pressure 030304 developmental biology Aged Retrospective Studies 0303 health sciences Training set business.industry Reproducibility of Results Middle Aged medicine.disease Sensory Systems Visual field Absolute deviation 030221 ophthalmology & optometry Visual Field Tests Female Visual Fields business Algorithms Test data Follow-Up Studies |
| Zdroj: | The British journal of ophthalmology. 104(5) |
| ISSN: | 1468-2079 |
| Popis: | AimsTo predict Humphrey Field Analyzer Central 10-2 Swedish Interactive Threshold Algorithm-Standard test (HFA 10-2) results (Carl Zeiss Meditec, San Leandro, CA) from HFA 24-2 results of the same eyes with advanced glaucoma.MethodsTraining and testing HFA 24-2 and 10-2 data sets, respectively, consisted of 175 eyes (175 patients) and 44 eyes (44 patients) with open advanced glaucoma (mean deviation of HFA 24-2 ≤−20 dB). Using the training data set, the 68 total deviation (TD) values of the HFA 10-2 test points were predicted from those of the innermost 16 HFA 24-2 test points in the same eye, using image processing or various machine learning methods including bilinear interpolation (IP) as a standard for comparison. The absolute prediction error (PredError) was calculated by applying each method to the testing data set.ResultsThe mean (SD) test–retest variability of the HFA 10-2 results in the testing data set was 2.1±1.0 dB, while the IP method yielded a PredError of 5.0±1.7 dB. Among the methods tested, support vector regression (SVR) provided a smallest PredError (4.0±1.5 dB). SVR predicted retinal sensitivity at HFA 10-2 test points in the preserved ‘central isle’ of advanced glaucoma from HFA 24-2 results of the same eye within an error range of about 25%, while error range was approximately twice of the test–retest variability.ConclusionApplying SVR to HFA 24-2 results allowed us to predict TD values at HFA 10-2 test points of the same eye with advanced glaucoma with an error range of about 25%. |
| Databáze: | OpenAIRE |
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