Prognostic factors in pathological stage IB nonsmall cell lung cancer greater than 3 cm
| Autor: | Yu Chung Wu, S.-F. Lin, Teh Ying Chou, Jung Jyh Hung, Chih-Cheng Hsieh, Wen Hu Hsu, Wen Juei Jeng, B.-S. Huang, M.-H. Huang, Jung-Sen Liu |
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| Rok vydání: | 2010 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine medicine.medical_specialty Lung Neoplasms TNM staging system Gastroenterology Stage ib Carcinoma Non-Small-Cell Lung Internal medicine medicine Humans Neoplasm Invasiveness Lung cancer Pathological Aged Neoplasm Staging Retrospective Studies business.industry Smoking Respiratory disease Cancer Middle Aged Prognosis medicine.disease respiratory tract diseases Surgery Survival Rate Tumour size Pleura Female Lymph Nodes Non small cell business |
| Zdroj: | European Respiratory Journal. 36:1355-1361 |
| ISSN: | 1399-3003 0903-1936 |
| DOI: | 10.1183/09031936.00014109 |
| Popis: | Significant heterogenity of stage IB (sixth edition of the TNM staging system) nonsmall cell lung cancer (NSCLC) has been identified, and further subclassification according to tumour size has been proposed. The aim of this study is to evaluate the prognostic factors in patients with resected stage IB NSCLC3 cm. From January 1980 to December 2000, 525 patients underwent surgical resection for stage IB NSCLC3 cm at Taipei Veterans General Hospital, Taipei, Taiwan. The clinicopathological characteristics of these patients were retrospectively reviewed. The 5- and 10-yr overall survival rates were 44.9% and 27.3%, respectively. Age (p0.001), tumour size (p = 0.002), extent of pulmonary resection (p = 0.002), histological type (p = 0.005) and number of mediastinal lymph nodes dissected/sampled (p = 0.004) were significant predictors for overall survival in multivariate analysis. Patients with tumour size7 cm, or5 to ≤ 7 cm, had a worse survival than those with tumour size3 to ≤ 5 cm. However, visceral pleural invasion did not influence overall survival. Stage IB NSCLC with a diameter3 cm may be subclassified according to tumour size regardless of visceral pleural invasion. |
| Databáze: | OpenAIRE |
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