Uncertainty in the Perioperative Management of High-Risk Cutaneous Squamous Cell Carcinoma Among Mohs Surgeons
| Autor: | Daniel Berg, Anokhi Jambusaria-Pahlajani, Kenneth A. Katz, Stephen D. Hess, Chrysalyne D. Schmults |
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| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
Skin Neoplasms medicine.medical_treatment Sentinel lymph node Perineural invasion MEDLINE Dermatology Risk Factors medicine Mohs surgery Carcinoma Humans Neoplasm Invasiveness Practice Patterns Physicians' Referral and Consultation Sentinel Lymph Node Biopsy business.industry Data Collection General surgery General Medicine Perioperative Mohs Surgery medicine.disease Surgery Clinical trial Radiation therapy Carcinoma Squamous Cell Radiotherapy Adjuvant Neoplasm Recurrence Local business |
| Zdroj: | Archives of Dermatology. 146:1225-1231 |
| ISSN: | 0003-987X |
| DOI: | 10.1001/archdermatol.2010.323 |
| Popis: | Objective To evaluate whether Mohs surgeons' management of high-risk cutaneous squamous cell carcinoma (HRCSCC) is uniform regarding radiologic nodal staging (RNS) and adjuvant radiation therapy (ART). Design A survey study of randomly selected, fellowship-trained Mohs surgeons. Setting An academic medical center. Participants American College of Mohs Surgery members who responded to an e-mail invitation completed either a survey regarding management of HRCSCC (n = 117) or SCC with perineural invasion (PNI) (n = 118). Participants totaled approximately 25% of the American College of Mohs Surgery membership. Main Outcome Measures (1) Percentage of patients with HRCSCC referred for RNS, sentinel lymph node biopsy (SLNB), or ART over the preceding 12 months; (2) top factors leading surgeons to consider RNS, SLNB, or ART; and (3) acceptance of ART for clinical scenarios of various degrees of PNI. Results Most respondents cited PNI and in-transit metastasis as top factors leading to consideration of RNS, SLNB, or ART. Otherwise, there was no consensus regarding use of, or indications for, RNS, SLNB, or ART. Conclusions The lack of consistency between experts indicates that there is equipoise regarding indications for RNS and ART in HRCSCC. There is also wide variation in RNS and ART practices among Mohs surgeons who are specifically trained to manage HRCSCC. Clinical trials should therefore be conducted in these areas as there is no clear standard of care. |
| Databáze: | OpenAIRE |
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