Evaluation of colonoscopic allergen provocation as a diagnostic tool in dogs with proven food hypersensitivity reactions
| Autor: | Shelly L. Vaden, Marcus G. Doherr, T. S. Harris, F. Gaschen, A. Gröne, Karin Allenspach, M. E. Griot-Wenk, Stephan C. Bischoff |
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| Rok vydání: | 2006 |
| Předmět: |
Male
Allergy medicine.medical_specialty Oral challenge test Colon Provocation test medicine.disease_cause Dogs Allergen Food allergy Animals Medicine Clinical significance Dog Diseases Small Animals business.industry digestive oral and skin physiology Colonoscopy Allergens Immunoglobulin E medicine.disease Food hypersensitivity Dermatology Case-Control Studies Sensitivity testing Immunology Female business Food Hypersensitivity |
| Zdroj: | Journal of Small Animal Practice. 47:21-26 |
| ISSN: | 0022-4510 |
| DOI: | 10.1111/j.1748-5827.2006.00007.x |
| Popis: | OBJECTIVE: To evaluate the colonoscopic allergen provocation (COLAP) test as a new tool for the diagnosis of IgE-mediated food allergy. METHODS: Oral food challenges as well as COLAP testing were performed in a colony of nine research dogs with proven immediate-type food allergic reactions. In addition, COLAP was performed in five healthy dogs. RESULTS: When compared with the oral challenge test, COLAP accurately determined 18 of 23 (73 per cent) positive oral challenge reactions (73 per cent) in dogs with food allergies and was negative in the healthy dogs. CLINICAL SIGNIFICANCE: The accuracy of this new test may be higher than that for gastric sensitivity testing. Therefore, COLAP holds promise as a new test to confirm the diagnosis of suspect IgE-mediated food allergy in dogs. |
| Databáze: | OpenAIRE |
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