Frequency of nasopharyngeal swab collection and positivity for SARS-CoV-2 infection in the population of the Italian province of Udine with and without chronic conditions
Autor: | Giada Mazzilis, Corrado Pipan, Anna Doimo, Francesca Valent |
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Rok vydání: | 2021 |
Předmět: |
Male
Chronic condition medicine.medical_specialty Adolescent Databases Factual Cross-sectional study Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Population Comorbidity Article COVID-19 Testing Nasopharynx Internal medicine Diabetes mellitus mental disorders Humans Medicine Statistics & numerical data Child education Aged Aged 80 and over education.field_of_study Reverse Transcriptase Polymerase Chain Reaction SARS-CoV-2 business.industry Health Policy Confounding Infant Newborn COVID-19 Infant Middle Aged medicine.disease Cross-Sectional Studies administrative database Italy real-time reverse-transcriptase polymerase chain reaction Child Preschool Female business chronic disease |
Zdroj: | Health Policy Health Policy (Amsterdam, Netherlands) |
ISSN: | 0168-8510 |
Popis: | Highlights • This is a prevalence study in the Italian province of Udine. • We study SARS-CoV-2 tests in persons with and without comorbidities. • Patients with comorbidities are tested more than the others. • Prevalence of positive test is not increased in patients with most chronic conditions. Severity of SARS-CoV-2 infection is associated with comorbidities. However, no information is available on the frequency of nasopharyngeal swab collection and positivity depending on comorbidities. Using a cross-sectional design, we assessed the prevalence of SARS-CoV-2 tests and of positivity in the general population of the 530,000-inhabitant Italian province of Udine and in subgroups affected by chronic conditions in the first weeks of SARS-CoV-2 epidemic. Anonymous health databases were used as source of information to identify persons with 14 chronic conditions. From laboratory records we assessed the likelihood of real‐time reverse‐transcriptase polymerase chain reaction for SARS-CoV-2 and the frequency of positivity from February 29 to April 19, 2020, i.e., 7 weeks from the first case detected in the study area. Sex and age-stratified proportions were calculated in comorbidity subgroups. Multivariate regression was used to adjust for confounders. In the province, 236,623 persons had ≥1 chronic condition; 869 had positive tests. Persons with comorbidities were tested more than the others. However, most chronic conditions were not significantly associated with the prevalence of positivity, except psychiatric and neurological diseases and diabetes. In conclusion, despite more frequent testing, patients with most chronic diseases where equally likely to be diagnosed with SARS-CoV-2 as the general population. Chronic patients should adhere to general recommendations for preventing SARS-CoV-2 infection, but ad hoc restrictions do not seem necessary. |
Databáze: | OpenAIRE |
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