Bed rest and other determinants of bone loss during pregnancy
| Autor: | Margaret Schramm, Joanne H. E. Promislow, John J.B. Anderson, Irva Hertz-Picciotto, Margaret Watt-Morse |
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| Rok vydání: | 2004 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent Pregnancy Trimester Third medicine.medical_treatment Prenatal care Weight Gain Bed rest Sensitivity and Specificity Bone Density Pregnancy Humans Medicine Prospective Studies Prospective cohort study Bone mineral business.industry Obstetrics Obstetrics and Gynecology medicine.disease Surgery Calcium Dietary Pregnancy Trimester First Trabecular bone Gestation Female business Bed Rest Maternal Age |
| Zdroj: | American Journal of Obstetrics and Gynecology. 191:1077-1083 |
| ISSN: | 0002-9378 |
| Popis: | Objective The purpose of this study was to evaluate patterns of bone loss during pregnancy and potential influences. Study design This was a prospective study of 181 women receiving prenatal care at Magee-Womens Hospital or its auxiliary clinics in Pittsburgh, Pennsylvania, between 1992 and 1995. Bone mineral density was measured at approximately 16 and 36 weeks' gestation. Results Trabecular, but not cortical, bone loss occurred during pregnancy. Mean ultra-distal bone mineral density loss was 1.9% (95% CI 1.2-2.5) during the 20-week period. Women prescribed bed rest had an adjusted mean loss of 4.6% compared with 1.5% for women not prescribed bed rest (P = .001) and 6-fold higher odds (P = .001) of bone loss ≥5% during the 20-week period. Nulliparity, calcium intake 30 years were more modestly associated with greater bone loss. Conclusion Substantial trabecular bone loss may occur during pregnancy, particularly in women prescribed bed rest. Study of postpartum bone recovery in such women is needed. |
| Databáze: | OpenAIRE |
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