Treatment with tucumã oil (Astrocaryum vulgare) for diabetic mice prevents changes in seric enzymes of the purinergic system: Improvement of immune system
| Autor: | Silvia Gonzalez Monteiro, Daniela B.R. Leal, Matheus D. Baldissera, Carine F. Souza, Thirssa H. Grando, Michele Rorato Sagrillo, Pedro H. Doleski, Aleksandro S. Da Silva |
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| Rok vydání: | 2017 |
| Předmět: |
Blood Glucose
0301 basic medicine Adenosine Arecaceae Pharmacology Oral gavage Diabetes Mellitus Experimental Mice 03 medical and health sciences 0302 clinical medicine Immune system Aminohydrolases Alloxan Animals Plant Oils Medicine 5'-Nucleotidase chemistry.chemical_classification biology business.industry Purinergic receptor Diabetic mouse General Medicine biology.organism_classification Astrocaryum vulgare 030104 developmental biology Enzyme chemistry Immune System Immunology Female business 030217 neurology & neurosurgery |
| Zdroj: | Biomedicine & Pharmacotherapy. 94:374-379 |
| ISSN: | 0753-3322 |
| DOI: | 10.1016/j.biopha.2017.07.113 |
| Popis: | The aim of this study was to evaluate the enzymatic activity of the purinergic system in sera samples from alloxan-induced diabetic mice treated with tucuma oil (Astrocaryum vulgare). For this, the mice were divided into four groups (n = 6): control/water (the group CW); control/tucuma oil (the group CT); diabetic/water (the group DW), and diabetic/tucuma oil (the group DT) treated for 14 days with 5.0 mL kg−1 via oral gavage. On day 14 post-treatment, mice were submitted to euthanasia and blood samples were collected by cardiac puncture. Tucuma oil treatment significantly decreased (p |
| Databáze: | OpenAIRE |
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