The light-oxygen effect in biological cells enhanced by highly localized surface plasmon-polaritons
| Autor: | Dmitrii Stoliarov, Igor O. Zolotovskii, Vladimir Sibirny, Vyacheslav V. Svetukhin, Evgenia Pogodina, Andrei A. Fotiadi, Edik U. Rafailov, Yury Saenko, Anna Khokhlova, Sergei G. Sokolovski |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Biophysics
lcsh:Medicine chemistry.chemical_element 02 engineering and technology Micro-optics medicine.disease_cause Oxygen Article law.invention 03 medical and health sciences 020210 optoelectronics & photonics 0302 clinical medicine law 0202 electrical engineering electronic engineering information engineering Polariton medicine Lasers LEDs and light sources Irradiation lcsh:Science chemistry.chemical_classification Reactive oxygen species Multidisciplinary lcsh:R Laser Biophotonics chemistry lcsh:Q Biological physics 030217 neurology & neurosurgery Oxidative stress Localized surface plasmon |
| Zdroj: | Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019) Scientific Reports |
| ISSN: | 2045-2322 |
| Popis: | Here at the first time we suggested that the surface plasmon-polariton phenomenon which it is well described in metallic nanostructures could also be used for explanation of the unexpectedly strong oxidative effects of the low-intensity laser irradiation in living matters (cells, tissues, organism). We demonstrated that the narrow-band laser emitting at 1265 nm could generate significant amount of the reactive oxygen species (ROS) in both HCT116 and CHO-K1 cell cultures. Such cellular ROS effects could be explained through the generation of highly localized plasmon-polaritons on the surface of mitochondrial crista. Our experimental conditions, the low-intensity irradiation, the narrow spectrum band (nm) of the laser and comparably small size bio-structures (~10 μm) were shown to be sufficient for the plasmon-polariton generation and strong laser field confinement enabling the oxidative stress observed. |
| Databáze: | OpenAIRE |
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