Cholangiocarcinoma, 10-Year Survival After Liver Transplantation: A Case Report
| Autor: | Natalia Zambudio Carroll, Jesus Maria Villar del Moral, Irina Palomo Lopez, Esther Brea Gomez, Antonio Becerra Massare, Maria Angeles Herrero Torres, María Trinidad Villegas Herrera, Julio Santoyo Villalba, Mireia Dominguez Bastante, Andrea Molina Raya |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Carcinoma Hepatocellular medicine.medical_treatment Liver transplantation Gastroenterology Cholangiocarcinoma Internal medicine medicine Overall survival Neoplasm Humans In patient Intrahepatic Cholangiocarcinoma Neoadjuvant therapy Aged Transplantation business.industry Liver Neoplasms medicine.disease Prognosis Liver Transplantation Bile Ducts Intrahepatic Bile Duct Neoplasms Hepatocellular carcinoma Surgery Female business Adjuvant |
| Zdroj: | Transplantation proceedings. 52(2) |
| ISSN: | 1873-2623 |
| Popis: | Cholangiocarcinoma is the second most common neoplasm in the liver, with a very poor, short-term prognosis. Today, surgery associated with or without an adjuvant is the only curative treatment. Liver transplantation (LT) is the best treatment for hepatocellular carcinoma tumor. In recent years, treatment of hilar cholangiocarcinoma by LT associated with neoadjuvant therapy has been studied under a criterion. But could it be possible to apply LT like the curative treatment of intrahepatic cholangiocarcinoma (iCC)? Initially the answer is no, but there are different studies about incidental LT in patients with iCC that demonstrate survival over 40% to 50%. In our center, we conducted a review of 468 transplants completed between 2002 and 2018, and we identified 1 case of incidental LT in a patient with iCC with an overall survival of 10 years. Because there is currently an increase in donors owing to the expansion of the criteria, a study to consider extending the criteria of LT to include iCC would be beneficial. |
| Databáze: | OpenAIRE |
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