Sequence analysis of four caprine mitochondria DNA lineages
| Autor: | Jin-Fang Xie, Yan-Ping Wu, Yue-Hui Ma, Wei-Jun Guan, Jun-Hong Huo |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Genetics
Mitochondrial DNA Transition (genetics) 040301 veterinary sciences Sequence analysis 0402 animal and dairy science Single-nucleotide polymorphism 04 agricultural and veterinary sciences Biology 040201 dairy & animal science Genome 0403 veterinary science Goat Mitochondrial genome Phylogenetics Coding region Animal Science and Zoology lcsh:Animal culture Transversion Human mitochondrial DNA haplogroup lcsh:SF1-1100 |
| Zdroj: | Italian Journal of Animal Science, Vol 11, Iss 4, Pp e69-e69 (2012) |
| ISSN: | 1594-4077 |
| Popis: | The complete mitochondrial DNA (mtDNA) (16640bp in length) was sequenced from four Chinese goat lineages representing the four major mtDNA haplogroups in goats. A total of 124 single nucleotide polymorphisms (SNPs) were found in encoding regions, and the overall ratio of transitions:transversions was 40:1 revealing a heavy transition/transversion rate in domestic goats. Eighteen non-synonymous sites were found for the total number of SNPs; the sites did not affect the predicted functions of protein for these four goat mtDNA lineages. In the region for coding tRNA and rRNA, SNPs occurred in loops, unstructured single strand and stems that were conformed with the principle of G-U pairing. We came to the conclusion that these substitutions could not change secondary structure of RNAs, and there was no positive selection on goat mitochondrial coding region according to the result of dN/dS (0.0399-0.1529) by comparing the goat with other reported mitochondrial genomes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
| Nepřihlášeným uživatelům se plný text nezobrazuje | K zobrazení výsledku je třeba se přihlásit. |