Safety of rAAV2/2-ND4 Gene Therapy for Leber Hereditary Optic Neuropathy
| Autor: | Nitza Thomasson, Serge Fitoussi, Sandrine Meunier, Jean-François Girmens, Barrett Katz, Bernard Gilly, Anne Galy, José-Alain Sahel, Samuel Bidot, Jean Philippe Combal, Sonia Valero, Laure Blouin, Céline Bouquet, Scott Uretsky, Catherine Vignal |
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| Přispěvatelé: | Fondation Ophtalmologique Adolphe de Rothschild [Paris], Centre d'investigation clinique Quinze-Vingts [CHNO] (CIC1423 - CIC QUINZE-VINGTS), Institut Hospitalo-Universitaire FOReSIGHT, Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts (CHNO)-Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts (CHNO)-Sorbonne Université (SU), Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts (CHNO), GenSight Biologics, Institut de la Vision, Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), University of Pittsburgh School of Medicine, Pennsylvania Commonwealth System of Higher Education (PCSHE), University of Pittsburgh Medical Center [Pittsburgh, PA, États-Unis] (UPMC), Marazova, Katia |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Male
LEBER HEREDITARY OPTIC NEUROPATHY Genetic enhancement [SDV]Life Sciences [q-bio] Genetic Vectors Visual Acuity Visual Physiology MEDLINE Optic Atrophy Hereditary Leber [SDV.GEN] Life Sciences [q-bio]/Genetics Bioinformatics Contrast Sensitivity 03 medical and health sciences 0302 clinical medicine Electroretinography medicine Humans Prospective Studies Prospective cohort study [SDV.GEN]Life Sciences [q-bio]/Genetics Color Vision medicine.diagnostic_test business.industry NADH Dehydrogenase Genetic Therapy Dependovirus Middle Aged Clinical trial [SDV] Life Sciences [q-bio] Ophthalmology Intravitreal Injections 030221 ophthalmology & optometry Evoked Potentials Visual Female business 030217 neurology & neurosurgery |
| Zdroj: | Ophthalmology: Journal of The American Academy of Ophthalmology Ophthalmology: Journal of The American Academy of Ophthalmology, 2018, 125 (6), pp.945-947. ⟨10.1016/j.ophtha.2017.12.036⟩ |
| ISSN: | 0161-6420 |
| DOI: | 10.1016/j.ophtha.2017.12.036⟩ |
| Popis: | International audience; No abstract available |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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