Incidence of benign pathology in patients undergoing hepatic resection for suspected malignancy

Autor:	Rowan W. Parks, Damian L. Clarke, O.J. Garden, K.K. Madhavan, R.A.E. Clayton, E.J. Currie
Rok vydání:	2003
Předmět:	Adult Liver Cirrhosis Male medicine.medical_specialty medicine.medical_treatment Bile Duct Neoplasm Malignancy Risk Assessment Preoperative care Metastasis Cohort Studies Diagnosis Differential Age Distribution Preoperative Care Biopsy Hepatectomy Humans Medicine Prospective Studies Sex Distribution Aged Cholangiopancreatography Endoscopic Retrograde medicine.diagnostic_test business.industry Bile duct Incidence Biopsy Needle Liver Neoplasms Middle Aged medicine.disease Immunohistochemistry Surgery medicine.anatomical_structure Bile Duct Neoplasms Liver Female Differential diagnosis Tomography X-Ray Computed business Ireland
Zdroj:	The Surgeon. 1:32-38
ISSN:	1479-666X
Popis:	Background: Confirming the presence of hepatic or proximal bile duct malignancy pre-operatively remains difficult and some patients may undergo surgical resection for suspected malignant lesions which subsequently turn out to be benign. The aim of this study was to establish whether improvements in pre-operative staging might better identify this patient population. Methods : Analysis of a prospectively collected database, which has been maintained in our unit since 1988. Results : Of 250 consecutive patients undergoing hepatic resection for presumed malignancy, 18 (7.2%) were shown to have benign pathology. These "false positive" rates were 4 out of 160 (2.5%) resections for colorectal metastases, 4 out of 49 (8.2%) resections for other solid hepatobiliary tumours and 10 out of 41 (24.4%) resections for hilar cholangiocarcinoma. Four of the 18 patients (22%) developed post-operative complications but there was no postoperative mortality. Conclusion : Although hepatic resection remains a potentially curative procedure for patients with tumours involving the liver parenchyma or proximal bile ducts, pre-operative confirmation of malignancy remains difficult. Despite appropriate investigation a subset of patients with benign disease will still be subjected to major hepatic resection which should be undertaken in a specialist unit
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e89a78e9d3074bae9d0018c4925055e https://doi.org/10.1016/s1479-666x(03)80006-9 Zobrazit plný text záznamu Full Text from ScienceDirect Plný text ve formátu PDF Plný text ve formátu HTML
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