Two months auto-adjusting versus conventional nCPAP for obstructive sleep apnoea syndrome
| Autor: | Farhat Aa, N Konietzko, Thomas E. Wessendorf, Helmut Teschler, M Berthon-Jones |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Pulmonary and Respiratory Medicine
Adult Male Leak Home Nursing medicine.medical_treatment Polysomnography Positive pressure Pulmonary compliance Nose Positive-Pressure Respiration Double-Blind Method medicine Humans Continuous positive airway pressure Hypoxia Lung Compliance Obstructive sleep apnoea syndrome Aged Sleep Apnea Obstructive Cross-Over Studies medicine.diagnostic_test business.industry Masks Sleep apnea Middle Aged medicine.disease Crossover study respiratory tract diseases Anesthesia business |
| Zdroj: | The European respiratory journal. 15(6) |
| ISSN: | 0903-1936 |
| Popis: | Autoadjusting nasal continuous positive airway pressure (CPAP) greatly reduces the apnoea/hypopnoea index (AHI), and affords a significant reduction in median pressure (P50) compared-with manually titrated conventional nasal CPAP. The aim of the present study was to test whether these benefits were maintained in the medium term at home, in a double-blind crossover study. Ten sequential subjects (mean AHI 52.9 x h(-1)) were enrolled. After a manual titration, subjects were randomly allocated to 2 months autoadjusting nasal CPAP (AutoSet), followed by 2 months with the AutoSet device in fixed pressure mode at the manually titrated pressure, or vice versa. The machine-scored AHI, P50, and median leak were recorded on 12 nights in each arm, and averaged. Mean+/-SEM AHI was 4.0+/-0.3 x h(-1) in auto mode, and 3.7+/-0.3 x h(-1) in manual mode (NS). Mean+/-SEM P50 was 7.2+/-0.4 cmH2O auto, 9.4+/-0.6 cmH2O manual, average reduction 23+/-4% (p |
| Databáze: | OpenAIRE |
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