Low-density lipoprotein-cholesterol lowering in individuals at intermediate cardiovascular risk: Percent reduction or target level?

Autor: Fernando H. Y. Cesena, Raquel D. Conceição, Viviane A. Valente, Raul D. Santos, Márcio Sommer Bittencourt, Antonio G. Laurinavicius
Rok vydání: 2017
Předmět:
Cardiovascular event
Relative risk reduction
Adult
Male
medicine.medical_specialty
Statin
medicine.drug_class
Population
Hypercholesterolemia
Clinical Investigations
Low density lipoprotein cholesterol
030204 cardiovascular system & hematology
03 medical and health sciences
0302 clinical medicine
Risk Factors
Internal medicine
medicine
Secondary Prevention
Humans
030212 general & internal medicine
education
Aged
education.field_of_study
Atherosclerotic cardiovascular disease
business.industry
Anticholesteremic Agents
Incidence
Disease Management
General Medicine
Cholesterol
LDL

Middle Aged
Survival Rate
Target level
Cardiovascular Diseases
Number needed to treat
lipids (amino acids
peptides
and proteins)

Female
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Cardiology and Cardiovascular Medicine
business
Brazil
Follow-Up Studies
Forecasting
Zdroj: Clinical cardiology. 41(3)
ISSN: 1932-8737
Popis: BACKGROUND: Recommendations for blood cholesterol management differ across different guidelines. HYPOTHESIS: Lipid‐lowering strategies based on low‐density lipoprotein‐cholesterol (LDL‐c) percent reduction or target concentration may have different effects on the expected cardiovascular benefit in intermediate‐risk individuals. METHODS: We selected individuals between 40 and 75 years of age with 10‐year risk for atherosclerotic cardiovascular disease (ASCVD) between 5.0% and
Databáze: OpenAIRE