Update on Local Anesthetic Toxicity, Prevention and Treatment During Regional Anesthesia in Infants and Children
| Autor: | Sujana Dontukurthy, Joseph D. Tobias |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Local anesthetic toxicity
business.industry Continuous infusion Local anesthetic medicine.drug_class Review Pharmacologic Agent 03 medical and health sciences 0302 clinical medicine Bolus (medicine) 030202 anesthesiology Regional anesthesia Anesthesia Pediatrics Perinatology and Child Health Medicine Pharmacology (medical) Dosing business Adverse effect 030217 neurology & neurosurgery |
| Zdroj: | J Pediatr Pharmacol Ther |
| ISSN: | 1551-6776 |
| Popis: | Local anesthetic agents play a key role in the treatment and prevention of pain in children. Although generally safe and effective, as with any pharmacologic agent, adverse effects may occur with the administration of these medications. Systemic absorption or inadvertent systemic injection during bolus dosing or continuous infusion can result in local anesthetic systemic toxicity with life-threatening neurological and cardiac complications. The following article reviews the pharmacology of local anesthetic agents, outlines previous reports of systemic toxicity during regional anesthesia, and discusses prevention and treatment algorithms. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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