Coumarin-based fluorescent probe for the rapid detection of peroxynitrite 'AND' biological thiols

Autor:	Tony D. James, Shaun Reeksting, Jie Wang, Xue Tian, Luling Wu, Adam C. Sedgwick, Xiao-Peng He, Steven D. Bull, Hai Hao Han, Robin R. Groleau
Rok vydání:	2020
Předmět:	inorganic chemicals Analyte Chromatography General Chemical Engineering General Chemistry Glutathione Coumarin Fluorescence Rapid detection chemistry.chemical_compound chemistry cardiovascular system Fluorescence response Peroxynitrite
Zdroj:	RSC advances. 10(23)
ISSN:	2046-2069
Popis:	A coumarin-based novel ‘AND’ logic fluorescent probe ROS-AHC has been developed for the simultaneous detection of ONOO− and biological thiols. ROS-AHC was shown to exhibit only a very small fluorescence response upon addition of a single GSH or ONOO− analyte. Exposure to both analytes, however, resulted in a significant fluorescence enhancement.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e70fca1057d8a0fdd6224076ee8ed99 https://pubmed.ncbi.nlm.nih.gov/35493005 Zobrazit plný text záznamu