A quantitative approach to evaluate image quality of whole slide imaging scanners
| Autor: | R Kneepkens, Prarthana Shrestha, Esther Abels, Bas Hulsken, Dirk L. J. Vossen, J Vrijnsen |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Scanner Computer science Image quality media_common.quotation_subject Quantitative image quality Health Informatics Context (language use) lcsh:Computer applications to medicine. Medical informatics Pathology and Forensic Medicine 03 medical and health sciences 0302 clinical medicine lcsh:Pathology Computer vision Quality (business) scanner quality Reliability (statistics) media_common Reproducibility business.industry Computer Science Applications subjective image quality 030104 developmental biology 030220 oncology & carcinogenesis Assessment methods lcsh:R858-859.7 Original Article Artificial intelligence business Acceptable quality limit lcsh:RB1-214 |
| Zdroj: | Journal of Pathology Informatics, Vol 7, Iss 1, Pp 56-56 (2016) Journal of Pathology Informatics |
| ISSN: | 2153-3539 |
| Popis: | Context: The quality of images produced by whole slide imaging (WSI) scanners has a direct influence on the readers’ performance and reliability of the clinical diagnosis. Therefore, WSI scanners should produce not only high quality but also consistent quality images. Aim: We aim to evaluate reproducibility of WSI scanners based on the quality of images produced over time and among multiple scanners. The evaluation is independent of content or context of test specimen. Methods: The ultimate judge of image quality is a pathologist, however, subjective evaluations are heavily influenced by the complexity of a case and subtle variations introduced by a scanner can be easily overlooked. Therefore, we employed a quantitative image quality assessment method based on clinically relevant parameters, such as sharpness and brightness, acquired in a survey of pathologists. The acceptable level of quality per parameter was determined in a subjective study. The evaluation of scanner reproducibility was conducted with Philips Ultra-Fast Scanners. A set of 36 HercepTest™ slides were used in three sub-studies addressing variations due to systems and time, producing 8640 test images for evaluation. Results: The results showed that the majority of images in all the sub-studies are within the acceptable quality level; however, some scanners produce higher quality images more often than others. The results are independent of case types, and they match our perception of quality. Conclusion: The quantitative image quality assessment method was successfully applied in the HercepTest™ slides to evaluate WSI scanner reproducibility. The proposed method is generic and applicable to any other types of slide stains and scanners. |
| Databáze: | OpenAIRE |
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