Newcastle disease virus vaccine strains: Immunogenicity is not influenced by ICPI
| Autor: | L. Doretto Júnior, Orsi Ma, Lha da Silva, Fernando Rosado Spilki, Maria da Glória Buzinaro, Dilmara Reischak, Clarice Weis Arns |
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| Přispěvatelé: | National Agricultural Laboratory, Universidade Estadual de Campinas (UNICAMP), Avian Health Consultant, Feevale University Center, Universidade Estadual Paulista (Unesp) |
| Předmět: |
lcsh:Veterinary medicine
biology Immunogenicity Newcastle disease virus biology.organism_classification Pathogenicity Newcastle disease Virology mean death time (MDT) Vaccination Vaccine strain Virus vaccine Immunity lcsh:Zoology Newcastle disease virus (NDV) vaccines Potency lcsh:SF600-1100 Animal Science and Zoology lcsh:Animal culture lcsh:QL1-991 intracerebral pathogenicity index (ICPI) Aves lcsh:SF1-1100 |
| Zdroj: | Scopus-Elsevier Brazilian Journal of Poultry Science v.11 n.2 2009 Brazilian Journal of Poultry Science Fundação APINCO de Ciência e Tecnologia Avícolas (FACTA) instacron:FACTA Revista Brasileira de Ciência Avícola, Volume: 11, Issue: 2, Pages: 129-133, Published: JUN 2009 ResearcherID Brazilian Journal of Poultry Science, Vol 11, Iss 2, Pp 129-133 (2009) Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP |
| Popis: | Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:23:53Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:35:28Z : No. of bitstreams: 1 2-s2.0-70349432655.pdf: 93352 bytes, checksum: 920c49204f76f9d7dafb264f2e6c596e (MD5) Made available in DSpace on 2014-05-27T11:23:53Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-04-01 Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Intracerebral pathogenicity index (ICPI) and mean death time (MDT) were determined using commercial live vaccines against Newcastle disease available in Brazil. The ICPI profiles obtained for B1 vaccine strains were nonvirulent and varied from 0 to 0.19, and their MDT was 104-116 hours. The LaSota strains had an ICPI varying between 0.02 and 0.37 and MDT from 92 to 116 hours. ICPI and MDT for the Clone 30 were 0.11 and 104 hours, respectively. For Ulster vaccines, ICPI and MDT were 0 and >150 hours; for VG-GA was 0.03 and 140 hours; and for C2, 0.04 and >144 hours. Eye drop vaccination and IM challenge, at the 1 st week and the 4 th week, respectively, resulted in highest protection for B1 (95-100%) and LaSota (90-100%) strains. The variability in vaccine ICPI did not interfere with immune response and all vaccines provided similar protection. All vaccines were considered non virulent and were classified as lentogenic according to the immunobiological product standards. National Agricultural Laboratory - Lanagro/ SP, Campinas, SP Faculty of Medical Sciences University of Campinas - Unicamp, Campinas, SP Avian Health Consultant Feevale University Center, Novo Hamburgo, RS Departments of Preventive Medicine Faculty of Agricultural and Veterinary Sciences Paulista State University, Jaboticabal Campus, Jaboticabal, SP Laboratory of Virology Institute of Biology CP 6109, University of Campinas - Unicamp, 13083-970. Campinas, SP Departments of Preventive Medicine Faculty of Agricultural and Veterinary Sciences Paulista State University, Jaboticabal Campus, Jaboticabal, SP |
| Databáze: | OpenAIRE |
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