The prevalence and significance of nonuniform thyroid radio‐isotope uptake in patients with Graves’ disease

Autor:	Altayeb Abdalaziz, Ramesh Vanka, Peter Bartholomew, Nicholas Vennart, Jonathan Vernazza, Kathryn Stewart, Vasileios Tsatlidis, Kilimangalam Narayanan, Jolanta U Weaver, Salman Razvi
Rok vydání:	2022
Předmět:	Male Endocrinology Antithyroid Agents Isotopes Recurrence Endocrinology Diabetes and Metabolism Prevalence Humans Female Receptors Thyrotropin Middle Aged Graves Disease Autoantibodies
Zdroj:	Clinical Endocrinology. 97:100-105
ISSN:	1365-2265 0300-0664
Popis:	To evaluate the prevalence and clinical significance of nonuniform technetium (Patients with GD, referred between July 2005 and March 2018, had TcOf the 276 GD patients (mean age, 49.8 years; 84% female), 25 (9.0%) had nonuniform TcNonuniform radio-isotope uptake is seen in 1 in 11 patients with GD which could be misdiagnosed as toxic multinodular goitre if TRAb levels are not measured. Treatment of GD patients with nonuniform radio-isotope uptake with ATD therapy as first-line appears to be equally effective as compared with those with uniform uptake. TRAb testing should be the main diagnostic test for patients with suspected GD with radio-labelled uptake scans being reserved for those who are TRAb negative.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e6420cdb30db9b6181d6330ba08670d https://doi.org/10.1111/cen.14709 Zobrazit plný text záznamu Plný text