Facile synthesis of 1-trifluoromethylalkenes via the decarboxylation of α-trifluoromethyl-β-lactones
| Autor: | P. Veeraraghavan Ramachandran, Barnabas Otoo |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
chemistry.chemical_classification
Trifluoromethyl Hydrocarbons Fluorinated Decarboxylation Aryl Metals and Alloys General Chemistry Alkenes Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials Lactones chemistry.chemical_compound chemistry Materials Chemistry Ceramics and Composites Organic chemistry Stereoselectivity Alkyl |
| Zdroj: | Chemical Communications. 51:12388-12390 |
| ISSN: | 1364-548X 1359-7345 |
| DOI: | 10.1039/c5cc03230j |
| Popis: | DCC-mediated cyclodehydration of α-trifluoromethyl-β-hydroxy acids provides α-trifluoromethylated β-lactone intermediates, without loss of stereoselectivity. These lactones undergo facile decarboxylation providing a simple route to obtain both alkyl and aryl 1-trifluoromethyl alkenes in excellent yields and stereoselectivity. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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