Effect of added dietary threonine on growth performance, health, immunity and gastrointestinal function of weaning pigs with differing genetic susceptibility to Escherichia coli infection and challenged with E. coli K88ac
| Autor: | Stefano Messori, E. Corrent, Y. Gherpelli, Paolo Bosi, Paolo Trevisi, A. Simongiovanni, Davide Priori, Maurizio Mazzoni |
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| Přispěvatelé: | P. Trevisi, E. Corrent, M. Mazzoni, S. Messori, D. Priori, Y. Gherpelli, A. Simongiovanni, P. Bosi |
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Genetic Markers
Threonine L-threonine Globulin Swine Weaning Gut flora Feed conversion ratio digestive system Microbiology Andrology Jejunum Excretion Food Animals Immunity medicine Animals Genetic Predisposition to Disease Escherichia coli Infections Swine Diseases Pig biology Mucin-4 biology.organism_classification Animal Feed Antibodies Bacterial Diet Immunoglobulin A enterotoxigenic Escherichia coli K88 medicine.anatomical_structure Gene Expression Regulation Immunoglobulin M biology.protein Animal Science and Zoology Animal Nutritional Physiological Phenomena Gastrointestinal function |
| Popis: | Summary Threonine (Thr) is important for mucin and immunoglobulin production. We studied the effect of added dietary Thr on growth performance, health, immunity and gastrointestinal function of weaning pigs with differing genetic susceptibility to E. coli K88ac (ETEC) infection and challenged with ETEC. Forty-eight 24-day-old weaned pigs were divided into two groups by their ETEC susceptibility using mucin 4 (MUC4) gene as a marker (2 MUC4−/−, not-susceptible, and 2 MUC4+/+, susceptible, pigs per litter). Within genotype, pigs were fed two different diets: 8.5 (LThr) or 9.0 (HThr) g Thr/kg. Pigs were orally challenged on day 7 after weaning and slaughtered on day 12 or 13 after weaning. Before ETEC challenge, HThr pigs ate more (p |
| Databáze: | OpenAIRE |
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