Disability and Recovery of Independent Function in Obstructive Lung Disease: The Cardiovascular Health Study

Autor: Vincent S. Fan, Rachel M Thomas, Stephen Thielke, Paul L. Enright, Gina S. Lovasi, Jerry A. Krishnan, Paula Diehr, Anthony Wilsdon, Mark V Avdalovic, Vishesh K. Kapur, Graham Barr, Sachin Yende, Emily Locke
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Male
Activities of daily living
Outcome Assessment
Respiratory System
Psychological intervention
Chronic airflow obstruction
Cardiorespiratory Medicine and Haematology
Severity of Illness Index
Disability Evaluation
Pulmonary Disease
Chronic Obstructive

0302 clinical medicine
Activities of Daily Living
Outcome Assessment
Health Care

030212 general & internal medicine
Longitudinal Studies
Lung
Cardiac Rehabilitation
medicine.diagnostic_test
Rehabilitation
Obstructive lung disease
3. Good health
Cardiovascular Diseases
Respiratory
Female
Independent Living
Risk assessment
Pulmonary and Respiratory Medicine
Spirometry
medicine.medical_specialty
Chronic Obstructive
Motor Activity
Risk Assessment
Article
Pulmonary Disease
03 medical and health sciences
Clinical Research
Severity of illness
medicine
Humans
Muscle Strength
Aged
Disability
business.industry
Prevention
Recovery of Function
medicine.disease
United States
Health Care
030228 respiratory system
Relative risk
Physical therapy
Exercise Test
business
Independent living
Zdroj: Respiration; international review of thoracic diseases, vol 88, iss 4
Popis: Background: Chronic obstructive lung disease frequently leads to disability. Older patients may experience transitions between states of disability and independence over time. Objective: To identify factors associated with transition between states of disability and independent function in obstructive lung disease. Methods: We analyzed data on 4,394 participants in the Cardiovascular Health Study who completed prebronchodilator spirometry. We calculated the 1-year probability of developing and resolving impairment in ≥1 instrumental activity of daily living (IADL) or ≥1 activity of daily living (ADL) using transition probability analysis. We identified factors associated with resolving disability using relative risk (RR) regression. Results: The prevalence of IADL impairment was higher with moderate (23.9%) and severe (36.9%) airflow obstruction compared to normal spirometry (22.5%; p < 0.001). Among participants with severe airflow obstruction, 23.5% recovered independence in IADLs and 40.5% recovered independence in ADLs. In the adjusted analyses, airflow obstruction predicted the development of IADL, but not ADL impairment. Participants with severe airflow obstruction were less likely to resolve IADL impairment [RR 0.67 and 95% confidence interval (CI) 0.49-0.94]. Compared to the most active individuals (i.e. who walked ≥28 blocks per week), walking less was associated with a decreased likelihood of resolving IADL impairment (7-27 blocks: RR 0.81 and 95% CI 0.69-0.86 and Conclusions: Disability is common in older people, especially in those with severe airflow obstruction. Increased physical activity and muscle strength are associated with recovery. Research is needed on interventions to improve these factors among patients with obstructive lung disease and disability.
Databáze: OpenAIRE