Acidosis, non-invasive ventilation and mortality in hospitalised COPD exacerbations
| Autor: | Rhona Buckingham, Robert A. Stone, Nancy A. Pursey, Chris Roberts, Derek Lowe |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male medicine.medical_specialty medicine.medical_treatment Partial Pressure Pulmonary Disease Chronic Obstructive Forced Expiratory Volume medicine Humans Intensive care medicine Acidosis Aged Mechanical ventilation COPD business.industry Mortality rate Metabolic acidosis Carbon Dioxide Hydrogen-Ion Concentration medicine.disease Respiration Artificial United Kingdom Clinical trial Hospitalization Oxygen Respiratory acidosis Emergency medicine Breathing Female Acidosis Respiratory medicine.symptom business Epidemiologic Methods |
| Zdroj: | Thorax. 66(1) |
| ISSN: | 1468-3296 |
| Popis: | Background Reports of non-invasive ventilation (NIV) use in clinical practice reveal higher mortality rates than in corresponding randomised clinical trials. Aim To explore factors related to chronic obstructive pulmonary disease (COPD) admissions and NIV use that may explain some of the previously reported high mortality rates. Methods National UK audit of clinical care of consecutive COPD admissions from March to May 2008. Retrospective case note audit with prospective case ascertainment. Participating units completed a web-based audit proforma of process and outcomes of clinical care. Results 232 hospital units collected data on 9716 patients, mean age 73, 50% male. 1678 (20%) of those with gases recorded on admission were acidotic and another 6% became acidotic later. 1077 patients received NIV, 55% had a pH |
| Databáze: | OpenAIRE |
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