A dielectric method for measuring early and late reactions in irradiated human skin
| Autor: | Rainer Kolle, Mikko Tenhunen, Jouni Nuutinen, Marita Turunen, Taina Usenius, Tapani Lahtinen, Esko Alanen |
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| Rok vydání: | 1998 |
| Předmět: |
Adult
Pathology medicine.medical_specialty Materials science Erythema medicine.medical_treatment Breast Neoplasms Human skin Dielectric Photon field Electric Impedance medicine Humans Radiology Nuclear Medicine and imaging Postoperative Period Irradiation Inverse correlation Subcutaneous fibrosis Aged Skin integumentary system business.industry Dose-Response Relationship Radiation Hematology Middle Aged Radiation therapy Oncology Body Composition Female Radiodermatitis medicine.symptom Mastectomy Radical Nuclear medicine business Follow-Up Studies |
| Zdroj: | Radiotherapy and Oncology. 47:249-254 |
| ISSN: | 0167-8140 |
| DOI: | 10.1016/s0167-8140(97)00234-x |
| Popis: | Background and purpose : To measure the dielectric constant of irradiated human skin in order to test the feasibility of the dielectric measurements in the quantitation of acute and late radiation reactions. Materials and methods : The dielectric constant of irradiated breast skin was measured at an electromagnetic frequency of 300 MHz in 21 patients during postmastectomy radiotherapy. The measurements were performed with an open-ended coaxial line reflection method. The irradiation technique consisted of an anterior photon field to the lymph nodes and a matched electron field to the chest wall using conventional fractionation of five fractions/week to 50 Gy. Fourteen out of the 21 patients were remeasured 2 years later and the skin was palpated for subcutaneous fibrosis. Results : At 5 weeks the dielectric constant had decreased by 31 and 39% for the investigated skin sites of the photon and electron fields, respectively. There was a statistically significant inverse correlation between the mean dielectric constant and the clinical score of erythema. An unexpected finding was a decrease of the dielectric constant of the contralateral healthy skin during radiotherapy. Two years later a statistically significant positive correlation was found between the dielectric constant at the irradiated skin sites and the clinical score of subcutaneous fibrosis. Conclusions : Dielectric measurements non-invasively yield quantitative information concerning radiation-induced skin reactions. |
| Databáze: | OpenAIRE |
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