Novel Paramagnetic Contrast Agents for Molecular Imaging and Targeted Drug Delivery
Autor: | Anne M. Morawski, Samuel A. Wickline, Anne H. Schmeider, Huiying Zhang, Michael J. Scott, Shelton D. Caruthers, Gregory M. Lanza, Patrick M. Winter, K.C. Crowder |
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Rok vydání: | 2004 |
Předmět: |
Nanotubes
medicine.diagnostic_test Contrast Media Molecular Probe Techniques Pharmaceutical Science Magnetic resonance imaging Nanotechnology Contrast (music) Computational biology Biology Magnetic Resonance Imaging Magnetics Biopolymers Drug Delivery Systems Targeted drug delivery Molecular Probes Magnetic contrast Image Interpretation Computer-Assisted Drug delivery medicine Animals Humans Molecular imaging Molecular Biology Biotechnology |
Zdroj: | Current Pharmaceutical Biotechnology. 5:495-507 |
ISSN: | 1389-2010 |
DOI: | 10.2174/1389201043376544 |
Popis: | Molecular biology and genomic sciences are revealing the early biological signatures for many diseases. In response, the Molecular Imaging community is rapidly developing contrast agents to visualize the nascent pathological changes and to concomitantly deliver treatment directly to the site of disease. The evaluation, development and use of these new agents require a complementary understanding of contrast chemistry and imaging techniques. The fundamental issues surrounding magnetic contrast agent development, rational drug delivery, MR molecular imaging, and their interdependence are elucidated. |
Databáze: | OpenAIRE |
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