Novel Paramagnetic Contrast Agents for Molecular Imaging and Targeted Drug Delivery

Autor: Anne M. Morawski, Samuel A. Wickline, Anne H. Schmeider, Huiying Zhang, Michael J. Scott, Shelton D. Caruthers, Gregory M. Lanza, Patrick M. Winter, K.C. Crowder
Rok vydání: 2004
Předmět:
Zdroj: Current Pharmaceutical Biotechnology. 5:495-507
ISSN: 1389-2010
DOI: 10.2174/1389201043376544
Popis: Molecular biology and genomic sciences are revealing the early biological signatures for many diseases. In response, the Molecular Imaging community is rapidly developing contrast agents to visualize the nascent pathological changes and to concomitantly deliver treatment directly to the site of disease. The evaluation, development and use of these new agents require a complementary understanding of contrast chemistry and imaging techniques. The fundamental issues surrounding magnetic contrast agent development, rational drug delivery, MR molecular imaging, and their interdependence are elucidated.
Databáze: OpenAIRE