Updates in Diabetic Wound Healing, Inflammation, and Scarring
Autor: | Joshua Vorstenbosch, Sebastian Winocour, Nina Dasari, Anna J. Skochdopole, Austin Jiang, Jayer Chung, Edward M. Reece |
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Rok vydání: | 2021 |
Předmět: |
0301 basic medicine
medicine.medical_specialty integumentary system Angiogenesis business.industry Wound dehiscence Inflammation medicine.disease Surgery Review article 03 medical and health sciences 030104 developmental biology 0302 clinical medicine 030220 oncology & carcinogenesis Diabetes mellitus medicine medicine.symptom business Wound healing Pathological Glycemic |
Zdroj: | Semin Plast Surg |
ISSN: | 1535-2188 |
Popis: | Diabetic patients can sustain wounds either as a sequelae of their disease process or postoperatively. Wound healing is a complex process that proceeds through phases of inflammation, proliferation, and remodeling. Diabetes results in several pathological changes that impair almost all of these healing processes. Diabetic wounds are often characterized by excessive inflammation and reduced angiogenesis. Due to these changes, diabetic patients are at a higher risk for postoperative wound healing complications. There is significant evidence in the literature that diabetic patients are at a higher risk for increased wound infections, wound dehiscence, and pathological scarring. Factors such as nutritional status and glycemic control also significantly influence diabetic wound outcomes. There are a variety of treatments available for addressing diabetic wounds. |
Databáze: | OpenAIRE |
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