Long-Term Results of Dialysis Therapy with a Highly Permeable Membrane
| Autor: | S. Lavaud, J. P. Brunois, J. P. Melin, Jacques Chanard, O. Toupance |
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| Rok vydání: | 2008 |
| Předmět: |
medicine.medical_specialty
Dialysis Therapy medicine.medical_treatment Group ii Acrylic Resins Biomedical Engineering Urology Medicine (miscellaneous) Renal function Bioengineering Kidney Function Tests Permeability Intestinal absorption Blood Urea Nitrogen Biomaterials Renal Dialysis medicine Humans Semipermeable membrane Vitamin D Cellulose Blood urea nitrogen Minerals business.industry Membranes Artificial General Medicine Long term results Long-Term Care Surgery Intestinal Absorption Kidney Failure Chronic Hemodialysis business |
| Zdroj: | Artificial Organs. 6:261-266 |
| ISSN: | 1525-1594 0160-564X |
| Popis: | A five-year study of short-term dialysis using highly permeable polyacrylonitrile membrane AN 69 was started in March 1973 to compare the effects of AN 69 and Cuprophan membrane (CM). The time of dialysis was calculated for each patient on the basis of vitamin B12 clearance of the dialyzer and the residual glomerular filtration rate. For the study, 101 patients (38,555 dialysis sessions) who had been dialyzed for more than six months were selected. They were divided into three groups: Group I (n = 31) patients treated with AN 69 only; Group II (n = 31) patients treated with CM; Group III (n = 39) patients treated first with the CM and then with AN 69. Patients treated with AN 69 had higher levels of plasma urea but no particular metabolic disturbances were observed. The dialysis sessions were significantly better tolerated with AN 69 than with CM, however, the main advantage of using AN 69 is the shortening of dialysis time. The duration of dialysis was 9.5 +/- 0.2 hours per week with AN 69 and 16.4 +/- 0.2 hours per week with CM. Shortening of dialysis time permits better social rehabilitation of the patients. The shorter dialysis was not associated with any recognizable side effects that could be demonstrated by routine clinical and biological analysis. |
| Databáze: | OpenAIRE |
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