Visceral perceptions and gastric myoelectrical activity in healthy women and in patients with bulimia nervosa
| Autor: | Sarah S. Bingaman, Kenneth L. Koch, R. M. Stern, L. Tan |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent Physiology Gastric motility behavioral disciplines and activities Gastroenterology Reference Values Internal medicine mental disorders medicine Humans Upper gastrointestinal In patient Bulimia Myoelectric Complex Migrating Meal Gastric emptying Endocrine and Autonomic Systems Bulimia nervosa Stomach digestive oral and skin physiology Signal Processing Computer-Assisted Control subjects medicine.disease Self Concept medicine.anatomical_structure Gastric Emptying Female Psychology |
| Zdroj: | Neurogastroenterology & Motility. 10:3-10 |
| ISSN: | 1365-2982 1350-1925 |
| Popis: | UNLABELLED Bulimia nervosa remains a common eating disorder in young women. Little is known about upper gastrointestinal symptoms or gastric motility in patients with bulimia nervosa. The aim of this study was to measure gastric myoelectrical activity and hunger/satiety and stomach emptiness/fullness before and after a non-nutrient water load and solid-phase gastric emptying in hospitalized patients with bulimia nervosa (n = 12) and in healthy women (n = 13). Gastric myoelectrical activity was measured by means of cutaneous electrodes; visual analogue scales were used to measure perceptions of hunger/satiety and stomach emptiness/fullness. Before and after a standard water load the bulimia patients reported significantly greater stomach fullness and satiety compared with control subjects (P < 0.01). The percentage of gastric myoelectrical power in the normal 3 cpm range was significantly less in bulimics compared with controls. Power in the 1-2 cpm bradygastria range was significantly greater in bulimia patients before and after the water load compared with the control subjects (P < 0.05). Solid-phase gastric emptying studies using radio-isotope-labelled scrambled eggs showed the lag phase was shortened in the bulimic patients (16 +/- 4 min vs 31 +/- 4 min in controls, P < 0.01), but the percentage of meal emptied at 2 h was similar to control values. IN CONCLUSION bulimia patients had exaggerated perceptions of stomach fullness and satiety in response to water; and abnormal gastric myoelectrical activity and accelerated lag phase of gastric emptying were objective stomach abnormalities detected in hospitalized patients with bulimia nervosa. |
| Databáze: | OpenAIRE |
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