Comparative Content, Biological and Anticancer Activities of Heracleum humile Extracts Obtained by Ultrasound‐Assisted Extraction Method

Autor: Mustafa Ocal, Yasemin Celik Altunoglu, Simone Angeloni, Ahmed M. Mustafa, Giovanni Caprioli, Gokhan Zengin, Mehmet Yavuz Paksoy, Mehmet Cengiz Baloglu
Rok vydání: 2022
Předmět:
Zdroj: Chemistry & Biodiversity. 19
ISSN: 1612-1880
1612-1872
Popis: As the safety and effectiveness of synthetic drugs remain in doubt, researchers are trying to develop natural medicines from medicinal plants. Herein, ethyl acetate, methanol and water extracts from the Heracleum humile plant were obtained by an ultrasonic-assisted extraction process and the aim was to evaluate some biological effects of the extracts due to the limited data on the pharmacological properties of Heracleum humile in the literature. Weak antibacterial activity was observed on tested bacterial species. The minimum inhibitory concentration and the minimum bactericidal concentration values ranged from 250 to 500 μg/mL. In addition, cytotoxic activity was determined using the MTT test. The strongest findings were determined for ethyl acetate extract on the MDA-MB-231 cell lines at the 48
Databáze: OpenAIRE
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