Relationship between mitochondrial haplogroup and physiological responses to hypobaric hypoxia
| Autor: | Takayuki Nishimura, Yuka Egashira, Fumi Kishida, Midori Motoi, Shigeki Watanuki |
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| Rok vydání: | 2015 |
| Předmět: |
0301 basic medicine
Adult Male medicine.medical_specialty Physiology Partial Pressure Adaptation Biological Short Report Human Factors and Ergonomics Hypobaric hypoxia Biology Altitude Sickness DNA Mitochondrial Haplogroup Anthropology Physical Mitochondrial haplogroup 03 medical and health sciences Young Adult 0302 clinical medicine Altitude Japan Heart Rate Physiology (medical) Internal medicine Heart rate medicine Humans Orthopedics and Sports Medicine Altitude sickness Genetics Polymorphism Genetic Haplotype Public Health Environmental and Occupational Health 030229 sport sciences medicine.disease Mitochondria Oxygen SpO2 030104 developmental biology Endocrinology Haplotypes Anthropology Hypobaric chamber Skin Temperature Human mitochondrial DNA haplogroup |
| Zdroj: | Journal of Physiological Anthropology |
| ISSN: | 1880-6805 |
| Popis: | We aimed to investigate the relationship between mtDNA polymorphism and physiological responses to hypobaric hypoxia. The study included 28 healthy male students, consisting of 18 students in haplogroup D and 10 in haplogroup M7+G. Measurement sensors were attached to the participants for approximately 30 min in an environment with a temperature of 28 °C. After resting for 15 min, the programmed operation of the hypobaric chamber decreased the atmospheric pressure by 11.9 Torr every minute to simulate an increase in altitude of 150 m until 9.7 Torr (equivalent to 2500 m) and then decreased 9.7 Torr every minute until 465 Torr (equivalent to 4000 m). At each altitude, the pressure was maintained for 15 min and various measurements were taken. Haplogroup D showed higher SpO2 (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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