Ventilation/perfusion indices do not correlate with the difference between oxygen consumption measured by the Fick principle and metabolic monitoring systems in critically ill patients
| Autor: | Lindsay I. G. Worthley, Robert K. Webb, John Myburgh |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Adult
Male Pulmonary Circulation Critical Illness medicine.medical_treatment Critical Care and Intensive Care Medicine Ventilation/perfusion ratio Fick principle Oxygen Consumption Intensive care Tidal Volume Ventilation-Perfusion Ratio Humans Medicine Prospective Studies Least-Squares Analysis Tidal volume Aged Monitoring Physiologic Mechanical ventilation business.industry Middle Aged Oxygen tension Oxygen Breath Tests Anesthesia Breathing Female Blood Gas Analysis business Perfusion |
| Zdroj: | Critical Care Medicine. 20:479-482 |
| ISSN: | 0090-3493 |
| DOI: | 10.1097/00003246-199204000-00008 |
| Popis: | Objective To determine whether the difference between oxygen consumption (VO2) measured by metabolic gas monitoring systems and by the Fick principle is related to venous admixture, deadspace/tidal volume ratio, or alveolar-arterial oxygen tension gradient in critically ill patients. Design A prospective study. Setting An 11-bed general ICU in a 900-bed teaching hospital. Patients Twenty critically ill patients admitted to the ICU who required mechanical ventilation, right heart catheterization, and arterial and mixed venous gas measurements for normal clinical management. Results Thirty-three recordings were analyzed. The mean VO2 measured by the metabolic gas monitoring system was 308 +/- 63.9 (SD) mL/min and was significantly greater than the mean VO2 measured by the Fick principle of 284 +/- 72.0 mL/min. The difference between the two measurements of 24.3 +/- 47.6 mL/min correlated poorly with venous admixture (r2 = .0009), dead-space/tidal volume ratio (r2 = .0064) and alveolar-arterial oxygen tension gradient (r2 = .017). Conclusions If the difference in VO2 measured by metabolic gas monitoring systems and the Fick principle is due to intrapulmonary VO2 then in critically ill patients the ventilation/perfusion indices of venous admixture, deadspace/tidal volume ratio and alveolar-arterial oxygen tension gradient correlate poorly with intrapulmonary VO2. |
| Databáze: | OpenAIRE |
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