Usefulness of Left Atrial Emptying Fraction to Predict Ventricular Arrhythmias in Patients With Implantable Cardioverter Defibrillators

Autor: Mehran Kamali Sadeghian, Mischa T. Rijnierse, Albert C. van Rossum, Anne-Lotte C.J. van der Lingen, Peter M. van de Ven, Cornelis P. Allaart, Robin Nijveldt, Sophie Schuurmans Stekhoven, P. Stefan Biesbroek
Přispěvatelé: Cardiology, APH - Methodology, ACS - Heart failure & arrhythmias, Epidemiology and Data Science, ACS - Atherosclerosis & ischemic syndromes, ACS - Microcirculation
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Cardiomyopathy
Dilated
Male
Tachycardia
medicine.medical_specialty
Time Factors
Systole
medicine.medical_treatment
Vascular damage Radboud Institute for Health Sciences [Radboudumc 16]
Cardiomyopathy
Magnetic Resonance Imaging
Cine
030204 cardiovascular system & hematology
03 medical and health sciences
0302 clinical medicine
Heart Conduction System
Internal medicine
medicine
Humans
Heart Atria
030212 general & internal medicine
Retrospective Studies
Ejection fraction
Ischemic cardiomyopathy
business.industry
Hazard ratio
Middle Aged
Prognosis
medicine.disease
Implantable cardioverter-defibrillator
Defibrillators
Implantable
Primary Prevention
Heart failure
Tachycardia
Ventricular
Cardiology
Atrial Function
Left
Female
medicine.symptom
Cardiology and Cardiovascular Medicine
business
Follow-Up Studies
Zdroj: American Journal of Cardiology, 120(2), 243-250. Elsevier Inc.
Rijnierse, M T, Kamali Sadeghian, M, Schuurmans Stekhoven, S, Biesbroek, P S, van der Lingen, A L C, van de Ven, P M, van Rossum, A C, Nijveldt, R & Allaart, C P 2017, ' Usefulness of Left Atrial Emptying Fraction to Predict Ventricular Arrhythmias in Patients With Implantable Cardioverter Defibrillators ', American Journal of Cardiology, vol. 120, no. 2, pp. 243-250 . https://doi.org/10.1016/j.amjcard.2017.04.015
American Journal of Cardiology, 120, 243-250
American Journal of Cardiology, 120, 2, pp. 243-250
ISSN: 0002-9149
Popis: Contains fulltext : 176957.pdf (Publisher’s version ) (Open Access) Impaired left atrial emptying fraction (LAEF) is an important predictor of mortality in patients with heart failure. As it may reflect increased LV wall stress, it might predict ventricular arrhythmia (VA) specifically. This study evaluated the predictive value of LAEF assessed with cardiovascular magnetic resonance (CMR) imaging with respect to appropriate device therapy (ADT) for VA and compared its role with CMR assessed scar size and other risk factors. In total, 229 patients (68% male, 63 +/- 10 years, 61% ischemic cardiomyopathy) with LV ejection fraction median and scar size < median were at low risk (13% ADT at 5 years), whereas those with LAEF < median and scar size > median experienced 40% ADT at 5 years (log-rank p = 0.01). In conclusion, LAEF independently predicts ADT in patients with primary prevention ICDs. Combined assessment of LAEF and scar size identifies a group with low risk of ADT. Therefore, LAEF assessment could assist in risk stratification for VA to select patients with the highest benefit from ICD implantation.
Databáze: OpenAIRE
Externí odkaz: