Extended Eversion Carotid Endarterectomy: Computation of Hemodynamics
| Autor: | Igor Lekšan, Tomislav Ištvanić, Hrvoje Brkić, Radivoje Radić, Zvonimir Vrselja, Goran Ćurić |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Patient-Specific Modeling
medicine.medical_specialty medicine.medical_treatment External carotid artery Hemodynamics Carotid endarterectomy Restenosis medicine.artery Internal medicine medicine Humans Arterial Pressure Carotid Stenosis Endarterectomy Carotid business.industry General Medicine Blood flow Middle Aged medicine.disease Surgery Stenosis medicine.anatomical_structure Regional Blood Flow carotid endarterectomy circulation blood flow wall shear stress computational fluid dynamics cardiovascular system Cardiology Female Vascular Resistance Internal carotid artery Cardiology and Cardiovascular Medicine business Blood Flow Velocity Artery |
| Zdroj: | Annals of Vascular Surgery. 29:1598-1605 |
| ISSN: | 0890-5096 |
| DOI: | 10.1016/j.avsg.2015.05.034 |
| Popis: | Background Stroke prevention includes surgery for significant stenosis of internal carotid artery (ICA). Consensus on a standard approach lacks and one alternative approach is eversion carotid endarterectomy (eCEA). To overcome disadvantages of eCEA, we developed extended-eversion carotid endarterectomy (exeCEA). Aiming to investigate hemodynamics after different surgical approaches, we created computational fluid dynamics (CFD) models of exeCEA and eCEA with included progressing lumen narrowing, representation of artery restenosis at the incision line. Methods Blood flow velocities, volume flow rates, and wall shear stress (WSS) were established in carotid arteries from models of eCEA and exeCEA with included increasing groove (1, 1.5, 2, and 2.5 mm) at the “incision line”, under input pressure of 120 and 150 mm Hg. Results For the corresponding restenosis grade, models of exeCEA had a larger orifice toward ICA, lower blood flow velocities and higher volume flow rates in ICA, with lower volume flow rates in external carotid artery. WSS values in ICA of exeCEA models were lower than in eCEA models, later reaching the thrombotic range. Conclusions CFD showed better hemodynamic properties in exeCEA models, indicating presented approach might be better at preserving brain perfusion. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|