The natural course of early-onset atopic dermatitis in Taiwan: a population-based cohort study
| Autor: | W.J. Wang, Yann Jang Chen, D.D. Lee, S.-Y. Chu, Y.T. Chang, Chien Chih Chen, Han Nan Liu, Chian Yaw Hwang, T.-C. Hua |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Adolescent Taiwan Kaplan-Meier Estimate Dermatology Disease Dermatitis Atopic Cohort Studies Atopy Young Adult Risk Factors Humans Medicine Age of Onset Child Survival analysis Aged Asthma business.industry Remission Induction Infant Atopic dermatitis Middle Aged medicine.disease Child Preschool Cohort Female Age of onset business Cohort study |
| Zdroj: | British Journal of Dermatology. 170:130-135 |
| ISSN: | 0007-0963 |
| DOI: | 10.1111/bjd.12603 |
| Popis: | Summary Background Atopic dermatitis (AD) often manifests in early childhood and has variable disease course among individual patients. Previous studies regarding the natural course of AD have usually been of small sample size and were not based on nationwide populations. Objectives We aimed to find out the disease duration and remission rate of children with early-onset AD (onset in the first 2 years of life) in Taiwan, and to determine whether the presence of allergic rhinitis (AR) or asthma affects the disease course. Methods The patients with early-onset AD in a nationally representative cohort were selected using the National Health Insurance Research Database of Taiwan and were followed from birth to 10 years of age. Kaplan–Meier survival analysis was carried out to analyse the disease duration and remission of AD. Between-group analysis using the log-rank test was carried out to analyse the influence of risk factors on the disease course. Results Of the 1404 children with early-onset AD, 19·4% had disease duration |
| Databáze: | OpenAIRE |
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