Sudden cardiac death and sarcoidosis of the heart in a young patient
Autor: | Johannes Alexandre Lobrinus, Silke Grabherr, Morgane Jotterand, Katarzyna Michaud |
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Rok vydání: | 2017 |
Předmět: |
Adult
medicine.medical_specialty Sarcoidosis Biopsy Autopsy Cardiac sarcoidosis ddc:616.07 Sudden death Pathology and Forensic Medicine Sudden cardiac death 03 medical and health sciences Fatal Outcome 0302 clinical medicine Heart Conduction System Internal medicine medicine Humans 030216 legal & forensic medicine business.industry ddc:614.1 General Medicine medicine.disease Death Sudden Cardiac Granulomatous disease 030220 oncology & carcinogenesis Cardiology Etiology Female Electrical conduction system of the heart Cardiomyopathies Cardiology and Cardiovascular Medicine business |
Zdroj: | Cardiovascular Pathology, Vol. 28 (2017) pp. 18-20 |
ISSN: | 1054-8807 |
DOI: | 10.1016/j.carpath.2017.01.003 |
Popis: | Sarcoidosis is a granulomatous disease of unknown etiology affecting any organ, microscopically characterized by noncaseating granulomata. Cardiac involvement in sarcoidosis has been reported. It might be symptomatic or not and even revealed by sudden death. Heart conduction system is rarely investigated at autopsy, even in cases of sudden cardiac death. We present a case of a 32-year-old woman who died suddenly. The examination of the heart conduction system revealed a cardiac sarcoidosis that could explain the sudden death. The review of clinical data of the patient revealed some symptoms consistent/in agreement with this hypothesis. Cardiac sarcoidosis remains a diagnostic challenge and can be easily missed, clinically and pathologically. The retrospective analysis of clinical data and autopsy results of fatal and unusual cases might help to better understand sarcoidosis and its clinical presentations. Examination of the cardiac conduction system is crucial in selected cases of sudden cardiac death. |
Databáze: | OpenAIRE |
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