Fluctuations in Antibody Titers against Enterovirus D68 in Pediatric Sera Collected in a Community before, during, and after a Possible Outbreak
| Autor: | Akira Suzuki, Hidekazu Nishimura, Francois Marie Ngako Kadji, Suguru Ohmiya, Yukio Nagai, Hitoshi Oshitani, Hiroko Ito, Ko Sato, Michiko Okamoto |
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| Rok vydání: | 2020 |
| Předmět: |
Male
0301 basic medicine Microbiology (medical) Background information medicine.medical_specialty 030106 microbiology Antibodies Viral medicine.disease_cause Neutralization Disease Outbreaks 03 medical and health sciences 0302 clinical medicine Japan Immunity Epidemiology Enterovirus Infections medicine Humans 030212 general & internal medicine Child Respiratory Tract Infections Enterovirus D Human business.industry Infant Newborn Antibody titer Infant Outbreak General Medicine Antibodies Neutralizing Virology Hospitalization Infectious Diseases Child Preschool Enterovirus Female Seasons business Enterovirus D68 |
| Zdroj: | Japanese Journal of Infectious Diseases. 73:55-57 |
| ISSN: | 1884-2836 1344-6304 |
| Popis: | We previously reported a hospital-based epidemiological study on enterovirus (EV)-D68 infection among children during the autumn of 2015, which indirectly inferred an outbreak in Sendai, Japan. In this study, stocked sera of children (aged 0-6 years; without symptoms of infectious diseases) in the Sendai community collected during 4 periods (1 year before, 6 months before, immediately after, and 1 year after the possible outbreak period) were analyzed using the neutralization antibody titer assay to determine community children's immunity levels against EV-D68 infection. The immunity levels were confirmed to have increased during the possible outbreak period and to have gradually waned over 1 year without another outbreak. These results provide background information supporting the results of our previous hospital-based surveillance study. |
| Databáze: | OpenAIRE |
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