Influence of Stratum Corneum on the entire skin mechanical properties, as predicted by a computational skin model
| Autor: | Basile Audoly, Jean Lévêque |
|---|---|
| Přispěvatelé: | Chercheur indépendant, Institut Jean le Rond d'Alembert (DALEMBERT), Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS) |
| Rok vydání: | 2012 |
| Předmět: |
Periodicity
MESH: Periodicity 02 engineering and technology 030207 dermatology & venereal diseases 0302 clinical medicine Skin Physiological Phenomena Composite material MESH: Biomechanics integumentary system skin model Dermis Compression (physics) MESH: Predictive Value of Tests Biomechanical Phenomena skin folds medicine.anatomical_structure MESH: Skin Physiological Phenomena Deformation (engineering) medicine.medical_specialty Materials science 0206 medical engineering elastic modulus Dermatology Models Biological 03 medical and health sciences Stratum Corneum MESH: Computer Simulation Predictive Value of Tests Stratum corneum medicine Humans Computer Simulation Elastic modulus MESH: Humans MESH: Models Biological Elasticity (physics) MESH: Dermis 020601 biomedical engineering compression thickness Elasticity Skin Aging MESH: Skin Aging MESH: Elasticity Epidermis MESH: Epidermis [SDV.MHEP.DERM]Life Sciences [q-bio]/Human health and pathology/Dermatology |
| Zdroj: | Skin Research and Technology Skin Research and Technology, 2013, 19 (1), pp.42-6. ⟨10.1111/j.1600-0846.2012.00664.x⟩ Skin Research and Technology, Wiley, 2013, 19 (1), pp.42-6. ⟨10.1111/j.1600-0846.2012.00664.x⟩ |
| ISSN: | 1600-0846 0909-752X |
| DOI: | 10.1111/j.1600-0846.2012.00664.x⟩ |
| Popis: | Background/Purpose Skin mechanical properties are globally well described. The aim of this paper is to evaluate, by means of a numerical model, the influence of Stratum Corneum (SC) on skin folding resulting from an in-plane compression. Methods A computational skin model was developed where skin is divided into three layers (SC, epidermis and upper dermis, and deep dermis) of different thicknesses and elastic moduli. Skin surface deformation, consecutive to the application of a given surface compression, was computed by minimizing the mechanical energy of the multi-layered tissue. Influence of SC thickness and elastic modulus on skin buckling is presented. Results Varying both SC thickness and elastic modulus has a marked influence on both wavelength and amplitude of the skin's surface folds. These two parameters display a logarithmic variation versus SC elastic modulus. Conclusion Although representing about one hundredth of the total skin thickness, SC has a marked influence on the skin mechanical properties. |
| Databáze: | OpenAIRE |
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