Giant Ovarian Thecoma Associated with Meigs Syndrome: A Striking Case
| Autor: | Dimitra Kollia, Eleni Carvounis, Dionysios Dellaportas, Despoina Myoteri, Theodosios Theodosopoulos, Constantinos Nastos, George Gkiokas |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Ovarian Neoplasms
medicine.medical_specialty Pleural effusion business.industry Ascites Middle Aged medicine.disease Malignancy Primary tumor Abdominal mass Adnexal mass Ovarian tumor Treatment Outcome CA-125 Antigen medicine Meigs' syndrome Humans Meigs Syndrome Surgery Female Radiology medicine.symptom Thecoma Ovarian cancer business |
| Zdroj: | Chirurgia (Bucharest, Romania : 1990). 116 |
| ISSN: | 1221-9118 |
| Popis: | Introduction: Meigs syndrome consists of the presence of a benign ovarian tumor, ascites and pleural effusion, and the latter two subdued after surgical excision of the ovarian tumor. Elevated Ca-125 in this context is confusing and is reported only in a handful of cases. A rare but striking case with the above features is presented herein. Case Presentation: A 46-year-old woman with a giant pelvic/abdominal mass originating from her right adnexa, ascites and pleural effusion, with elevated Ca-125 (938 IU/mL) was treated with the presumptive diagnosis of stage IV ovarian cancer. Imaging modalities showed a 22 cm solid adnexal mass and the patient underwent total abdominal hysterectomy and bilateral salpigooophorectomy, omentectomy and drainage of 4L of ascetic fluid. Surprisingly, final histopathology was negative for malignancy, characterizing the primary tumor as ovarian thecoma. Ascites and pleural effusion resolved by the seventh postoperative day, setting the diagnosis of Meigs syndrome. Discussion: Meigs syndrome accounts for 1% of all ovarian tumors, however it should be considered in the differential diagnosis when clinicians come across the classic triad of the syndrome, even when Ca-125 is elevated. These patients have normal life expectancy with meticulous management, while pathophysiology of this condition remains uncertain in various points. |
| Databáze: | OpenAIRE |
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