Risk factors associated with the development of aspiration pneumonia in patients receiving radiotherapy for head and neck cancer: retrospective study
| Autor: | Sakiko Soutome, Thoshiyuki Saito, Noriko Nakao, Kensuke Tashiro, Takashi Ukai, Tadafumi Kurogi, Shimpei Morimoto, Masako Yoshimatsu, Masahiro Umeda, Yumiko Kawashita |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Aspiration pneumonia Pneumonia Aspiration 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine Mucositis Humans Medicine Retrospective Studies Hypopharyngeal Neoplasms business.industry Incidence (epidemiology) Head and neck cancer Hypopharyngeal cancer Retrospective cohort study 030206 dentistry medicine.disease Discontinuation Radiation therapy Otorhinolaryngology Head and Neck Neoplasms 030220 oncology & carcinogenesis business |
| Zdroj: | Head & Neck. 42:2571-2580 |
| ISSN: | 1097-0347 1043-3074 |
| Popis: | Background Patients with head and neck cancer who are receiving radiotherapy can develop aspiration pneumonia. Determination of the incidence of aspiration pneumonia and the associated risk factors could facilitate the identification of high-risk patients. Methods In this retrospective study, we determined the incidence of aspiration pneumonia in 357 patients receiving radiotherapy along with oral care for head and neck cancer. We also performed univariate and multivariable logistic regression analyses to investigate the risk factors for this complication. Results The incidence of aspiration pneumonia was 17.6%. Hypopharyngeal cancer, grade 3 oral mucositis, and nasogastric tube feeding were independent risk factors. Moreover, the development of aspiration pneumonia was one of the major effects on the discontinuation of radiotherapy. Conclusion Approximately, one-sixth of the patients developed aspiration pneumonia despite appropriate oral care during radiotherapy for head and neck cancer. Aspiration pneumonia during radiotherapy could adversely affect head and neck cancer management. |
| Databáze: | OpenAIRE |
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