Synthesis and Anti-Platelet Activity of Thiosulfonate Derivatives Containing a Quinone Moiety

Autor:	Patrice Vanelle, Khrystyna Bolibrukh, Vira Lubenets, Volodymyr Novikov, Thierry Terme, Svyatoslav Polovkovych, T. I. Halenova, Irina Nikolaeva, Omar Khoumeri, Olexiy Savchuk
Přispěvatelé:	Institut de Chimie Radicalaire (ICR), Aix Marseille Université (AMU)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)
Rok vydání:	2014
Předmět:	Anti-platelet activity Chemistry Stereochemistry Thiosulfonate Pharmaceutical Science Moiety [CHIM]Chemical Sciences Quinone Anti platelet Research Article
Zdroj:	Scientia Pharmaceutica Scientia Pharmaceutica, 2015, 83 (2), pp.221--231. ⟨10.3797/scipharm.1411-14⟩ Volume 83 Issue 2 Pages 221-231
ISSN:	2218-0532
DOI:	10.3797/scipharm.1411-14⟩
Popis:	International audience; Thiosulfonate derivatives based on quinones were synthesized for studying "structure-activity relationship" compounds with an acylated and a free amino-group. Anti-platelet activity of the synthesized compounds was determined and the influence of substituents on the activity of the derivatives was assessed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e19c5d8e0a29da16c9d3c48541736ef https://pubmed.ncbi.nlm.nih.gov/26839819 Zobrazit plný text záznamu