Clinical and radiological comparison of effects of platelet-rich plasma, hyaluronic acid, and corticosteroid injections on temporomandibular joint osteoarthritis

Autor: Sinem Gökçe Kütük, Mustafa Kütük, Muhammet Arslan, Gökçen Gökçe, Osman Kürşat Arikan, Yasemin Özkan
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Male
intraarticular drug administration
Visual Analog Scale
Osteoarthritis
triamcinolone acetonide
Triamcinolone Acetonide
Palpation
Temporomandibular joint
viscosupplement
Injections
Intra-Articular

law.invention
0302 clinical medicine
Randomized controlled trial
law
middle aged
Corticosteroid
Medicine
Hyaluronic Acid
030223 otorhinolaryngology
pathophysiology
temporomandibular joint disorder
Viscosupplements
medicine.diagnostic_test
Platelet-Rich Plasma
General Medicine
Pain scale
Middle Aged
Temporomandibular Joint Disorders
female
medicine.anatomical_structure
Anesthesia
Female
Adult
Visual analogue scale
medicine.drug_class
Hyaluronic acid
03 medical and health sciences
Platelet-rich plasma
Humans
controlled study
human
Glucocorticoids
business.industry
030206 dentistry
medicine.disease
Otorhinolaryngology
thrombocyte rich plasma
randomized controlled trial
glucocorticoid
Surgery
business
Popis: There are few studies in the literature that comparatively evaluate the use of intra-articular orticosteroids (CS), hyaluronic acid (HA), and platelet-rich plasma (PRP). In this study, the authors aimed to compare the clinical results of intraarticular CS, HA, and PRP injections in patients who presented to the authors’ clinic with temporomandibular joint (TMJ) pain and clinically diagnosed with TMJ-osteoarthritis. Patients were evaluated in 2 groups as those patients who felt pain on lateral (n ¼ 31), and posterior (n ¼ 43) palpation. Patients who were evaluated in the study were randomly assigned to 3 different treatment groups as Group 1 (PRP), Group 2 (HA), and Group 3 (CS). Pain felt on the TMJ on lateral and posterior palpation was assessed before treatment and every month for 3 months using a 5-point pain scale. Presence of crepitation, loss of function, and loss of strength were assessed before treatment and every month for 3 months. Significant changes were observed in the PRP and HA groups when the patients were evaluated according to the VAS scores evaluated at different follow-up times for TMJ pain on lateral palpation. Significant changes were observed in the PRP, HA, and CS groups when VAS scores were evaluated according to the patients’ follow-up times for TMJ pain on lateral palpation. In conclusion, the findings of this study have shown that intra-articular PRP injections decreased TMJ palpation pain more effectively compared with the HA and CS groups. © 2019 by Mutaz B. Habal, MD.
Databáze: OpenAIRE