Analysis of HLA antigen association with proliferative diabetic retinopathy

Autor: Desmond B. Archer, Kidd Mn, C J Maguire, P B Johnston, D Middleton, A A Greenfield, L Kennedy
Rok vydání: 1982
Předmět:
Zdroj: British Journal of Ophthalmology. 66:277-279
ISSN: 0007-1161
DOI: 10.1136/bjo.66.5.277
Popis: One hundred and thirteen patients with insulin dependent diabetes mellitus for at least 15 years were typed for 22 HLA antigens of the A and B series. Fifty-six patients had severe bilateral proliferative retinopathy and 57 had no retinopathy. There was no statistical difference in frequency of HLA antigens between the 2 groups of diabetic patients. There was a significantly higher frequency of HLA B15 and a significant lower frequency of HLA B14, B17 in the combined diabetic groups than in a control population of 200 normal blood donors.
Databáze: OpenAIRE