Insulin sensitivity, body composition and adipose depots following 12 w combined endurance and strength training in dysglycemic and normoglycemic sedentary men

Autor: Birgitte Nellemann, Hanne L. Gulseth, Ansgar Heck, Hans Jørgen Noreng, Tryggve H. Storås, Atle Bjørnerud, Guro Grøthe, Torgeir Holen, Jørgen Arendt Jensen, Anders Kielland, Daniel S. Tangen, Marius Adler Dahl, Hans Kristian Stadheim, Egil Ivar Johansen, Torgrim Mikal Langleite, Frode Norheim, Christian A. Drevon, Kåre I. Birkeland, Kristoffer Jensen Kolnes
Rok vydání: 2016
Předmět:
Zdroj: Archives of Physiology and Biochemistry. 122:167-179
ISSN: 1744-4160
1381-3455
DOI: 10.1080/13813455.2016.1202985
Popis: Context: Insulin resistance and dysglycemia are associated with physical inactivity and adiposity, and may be improved by exercise. Objective: Investigate the effect of exercise on insulin sensitivity, body composition and adipose depots in sedentary men with (n = 11) or without (n = 11) overweight and dysglycemia. Material and methods: Euglycemic-hyperinsulinemic clamp, ankle-to-neck MRI, MRS, muscle and adipose tissue biopsies before and after 12 weeks combined strength and endurance exercise. Results: Insulin sensitivity, VO2max, strength, whole-body and muscle fat content, and abdominal adipose depots were improved without obvious differences between normo- and dysglycemic men. Hepatic fat, waist circumference and subcutaneous adipose tissue were reduced in the dysglycemic group. For both groups plasma adiponectin was reduced, whereas IL-6 was unchanged. Visceral fat was preferentially lost compared with other adipose depots. Discussion and conclusion: Body composition, fat distribution and in...
Databáze: OpenAIRE
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