In vitro and in vivo release of histamine by contrast media in the rat

Autor:	Leite Mp, Leme Jg, de Moraes Cr
Rok vydání:	1975
Předmět:	Male Contrast Media Vascular permeability Stimulation Blood Pressure 030204 cardiovascular system & hematology Pharmacology In Vitro Techniques Sodium Chloride Histamine Release Capillary Permeability 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine In vivo Burimamide Medicine Animals Radiology Nuclear Medicine and imaging 030212 general & internal medicine Mast Cells Radiological and Ultrasound Technology business.industry Degranulation In vitro Stimulation Chemical Rats Diphenhydramine chemistry Depression Chemical Histamine H1 Antagonists Vascular Resistance business Histamine
Zdroj:	Acta radiologica: diagnosis. 16(2)
ISSN:	0567-8056
Popis:	Some contrast media are able to release histamine from isolated mast cells of the rat and produce degranulation of these cells. Such properties are fairly correlated with the ability to increase vascular permeability in vivo and to produce a drop in blood pressure. If histamine is similarly being released in humans many untoward effects of these agents referred to clinically might be thus explained.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e0060bd422842a88456212dd2cb7fd3 https://pubmed.ncbi.nlm.nih.gov/52284 Zobrazit plný text záznamu