A motor relay on ciliary tracks

Autor: Robert O'Hagan, Maureen M. Barr
Rok vydání: 2015
Předmět:
Zdroj: Nature Cell Biology. 17:1517-1519
ISSN: 1476-4679
1465-7392
DOI: 10.1038/ncb3279
Popis: A powerful combination of two-colour imaging in vivo, Fourier-filtered kymography and simulations provides a high-resolution view of kinesin-2 transport dynamics in cilia. This study reveals heterotrimeric kinesin-II as an 'obstacle-course runner' and homodimeric OSM-3 (KIF17) as a 'long-distance runner', and elucidates the 'baton handoff' between these two kinesin-2 motors on the microtubule track.
Databáze: OpenAIRE
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